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Updated: Jul 23, 2025

Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Manner
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Published on: December 10, 2015

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核包装组装依赖CHMP-7在没有BAF-LEM介导的孔封闭的情况下

Sarah R Barger1, Lauren Penfield2, Shirin Bahmanyar1

  • 1Yale University, Department of Molecular, Cellular, Developmental Biology, 266 Whitney Ave., New Haven, CT 06511.

bioRxiv : the preprint server for biology
|July 18, 2023
PubMed
概括

在C. elegans中,阻碍自身整合因子 (BAF) 和LEM域蛋白在二次变异过程中冗余地封闭核外 (NE) 孔. BAF-LEM结合和LEMD2-CHMP7的不同作用确保了NE的完整性,并防止了组件的故障.

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