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Updated: Jul 23, 2025

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TRPS1调节染色体的可访问性,以调节雌激素受体 (ER) 结合和ER目标基因表达在光线乳腺癌细胞

Thomas G Scott1, Kizhakke Mattada Sathyan2,3, Daniel Gioeli4

  • 1Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, United States of America.

bioRxiv : the preprint server for biology
|July 18, 2023
PubMed
概括

这项研究显示,TRPS1,一种在乳腺瘤中过度表达的蛋白质,调节数百个基因,包括那些参与雌激素信号传递的基因. 削弱TRPS1会影响细胞周期和预后,这表明它是乳腺癌的潜在治疗点.

关键词:
乳腺癌 乳腺癌 乳腺癌染色是一种染色素.雌激素受体的受体在 TRPS1 中.转录 翻译 翻译

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