GLIS3在甲状腺发育中的作用以及在甲状腺特异性Glis3KO小鼠中的基因表达调节中的作用

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Updated: Jul 23, 2025

An Ex vivo Culture System to Study Thyroid Development
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An Ex vivo Culture System to Study Thyroid Development

Published on: June 6, 2014

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Hong Soon Kang1, Sara A Grimm1, Xiao-Hui Liao2

  • 1National Institutes of Health.

Research square
|July 18, 2023
PubMed
概括

失去GLI-Similar 3 (GLIS3) 会影响甲状腺激素的产生,导致先天性甲状腺功能低下症. GLIS3活性由TSH/PKA通路调节,影响甲状腺激素生物合成基因.

关键词:
在GLIS3中使用GLIS3.通过TSH信号传递.甲状腺功能低下症 甲状腺功能低下症甲状腺发育 甲状腺发育甲状腺毛囊细胞的增殖甲状腺激素生物合成

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