在维生素D缺乏患者中探索智能粘附监测方法:试点可行性临床研究
Ki Young Huh1, Hwiwon Lee2, SeungHwan Lee1
1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Clinical and translational science
|July 18, 2023
概括
智能手表监测提供了一种可靠的方法来跟踪治疗坚持,在维生素D研究中显示一致的结果. 这项技术可以通过提供客观的坚持数据来提高临床试验的准确性.
科学领域:
- 临床试验 临床试验
- 数字健康数字健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 坚持治疗对于成功的结果和临床试验有效性至关重要.
- 当前的遵守监测方法可能缺乏稳定性.
- 需要新的技术来客观地评估患者的坚持.
研究的目的:
- 评估多种合规性监测方法的可靠性和一致性.
- 调查基于智能手表的新型监控系统的有效性.
- 为了比较电子日记,药物计数和智能手表监控的坚持数据.
主要方法:
- 进行了一项开放的,随机的,分散的临床试验.
- 参与者接受了12周的维生素D补充剂.
- 使用电子日记 (App) 和智能手表,以及药丸计数和血清25(OH) 维生素D水平来监测守.
主要成果:
- 血清25(OH) 维生素D水平在两组中都增加,在第二个时期的App + Watch组中趋势更高.
- 药片数量和App记录的剂量在第二期显示出显著差异 (p=0.0225).
- 智能手表监测在整个研究中显示出一致的一致性 (p=0.5898和p=0.5839).
结论:
- 基于智能手表的遵守监测似乎是一种客观而敏感的方法.
- 这项技术有可能提高临床试验合规性评估的准确性.
- 结合多种遵守监测方法,包括新的数字工具,对于稳健的数据收集至关重要.
相关概念视频
Chronic Kidney Disease IV: Nursing Management
26
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
26
Chronic Kidney Disease III: Interprofessional Care
43
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
43
Guidelines For Measuring Vital Signs
1.7K
Following these guidelines can help nurses accurately measure vital signs, assess changes in patient conditions, and provide timely treatment when necessary. Adhering closely to the guidelines ensures the accuracy and reliability of the results.
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.
1.7K
Role of Skin in Vitamin D Synthesis
5.3K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.3K
Chronic Kidney Disease II: Clinical Manifestations
35
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
35
Rheumatic Heart Disease IV: Nursing Management
18
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
18


