[用于早泄的不同时间窗口的复合香和利多卡因化凝:一项前性单中心随机对照研究]
Biao Cai1, Hong-Cai Cai1, Jin-Tao Zhuang1
1Department of Andrology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
Zhonghua nan ke xue = National journal of andrology
|July 18, 2023
概括
复合香和利多卡因化凝 (CCLH) 有效治疗早泄 (PE),显示在5分钟内迅速发作. 这种局部治疗显著改善了射精延迟和患者报告的结果,副作用最小.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 药理学 药理学是指药理学的学科.
背景情况:
- 早泄 (PE) 是一种常见的性功能障碍,影响了许多男性.
- 针对PE的有效和安全的治疗选择正在不断寻求.
研究的目的:
- 评估复合香和利多卡因化凝 (CCLH) 治疗早泄 (PE) 的疗效和安全性.
- 为了比较CCLH在不同性交前时间窗口 (5分钟与15分钟) 中应用的效果.
主要方法:
- 一项前性研究涉及72名PE患者,他们接受了局部CCLH治疗.
- 患者被随机分配到5分钟应用组 (n=39) 和15分钟应用组 (n=33).
- 阴道内射精潜伏时间 (IELT),PE诊断工具 (PEDT) 评分,生活质量和不良反应在治疗前和后被评估.
主要成果:
- 完成该研究的所有患者 (n=62) 在IELT (P < 0.01) 和PEDT得分 (P < 0.05) 中显著改善.
- 没有报告过敏反应或减少勃起硬度等显著不良影响;有些人甚至注意到硬度增加.
- 大多数患者 (57) 报告说没有阴茎麻木或减少性满意度,成功完成性活动.
结论:
- 复合香和利多卡因化凝 (CCLH) 是对早泄 (PE) 的有效治疗方法.
- 在性交前5分钟的应用窗口提供了快速开始的作用.
- CCLH表现出良好的安全性,没有发现显著的不良影响.
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