全心房导电时间作为心房复发的预测:系统性审查和元分析
Sotirios Chiotis1, Ioannis Doundoulakis2,3, Eirini Pagkalidou4
1From the Department of Cardiology, 424 Military Hospital, Thessaloniki, Greece.
Cardiology in review
|July 18, 2023
概括
通过心声学测量的全心房导电时间 (TACT) 预测了心律控制患者心房的复发情况. 长时间的TACT是显著的风险因素,特别是在心转动后的持续性AF中.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 电子生理学 电子生理学
背景情况:
- 在节律控制策略之后,心房动 (AF) 的复发是临床挑战.
- 预测AF复发的标志物对于指导治疗决策至关重要.
- 组织多普勒回声心脏图 (TDE) 提供了对心房功能的非侵入性评估.
研究的目的:
- 系统地审查和元分析AF复发的心房总导电时间 (TACT) 的预测值.
- 评估TACT使用PA-TDE在使用节律控制策略管理的患者中.
- 评估TACT在预测心脏转移或导管切除后AF复发方面的实用性.
主要方法:
- 在PubMed,Cochrane图书馆和科学网络的系统文献搜索.
- 包括7项遵循PRISMA指南的研究.
- 使用随机效应模型进行元分析,以比较TACT并估计其预测值 (MD,sAUC).
主要成果:
- 延长的TACT与AF复发有显著的相关性 (MD,23.12毫秒;95% CI,11.54-34.71).
- 亚组分析显示,在心转后持续性AF (MD, 26.56毫秒) 中存在强烈的关联,但在除血后的性AF中没有.
- 曲线下的总结面积 (sAUC) 表示良好的预测性能 (0.89).
结论:
- 整体心房传导时间 (TACT) 是一个有价值的心声学预测器的AF复发在接受节律控制的患者.
- TACT显示出显著的预测能力,特别是在持续的AF患者治疗电心转变.
- 进一步的研究可能会完善TACT在个性化AF管理策略中的作用.
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