扩散权重成像补充了T2权重的MRI,用于评估状癌状腺癌的瘤反应
Davide Prezzi1,2, Keerthini Muthuswamy3, Ashik Amlani3
1School of Biomedical Engineering and Imaging Sciences, King's College London, King's Health Partners, London, UK. davide.prezzi@kcl.ac.uk.
European radiology
|July 18, 2023
概括
扩散加权成像 (DWI) 显著降低了化学放射治疗的状门癌症的不确定的瘤反应得分. 将DWI添加到T2权重的MRI中也可以提高放射科医生对评估治疗有效性的信心.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 用化学放射治疗治疗状门癌症往往会导致不确定的瘤回归等级 (TRG) 在T2加权MRI上的得分.
- 这种模糊性使得早期评估治疗反应变得复杂.
研究的目的:
- 为了评估是否添加扩散权重成像 (DWI) 到T2权重的MRI提高瘤反应的评估在治疗后期早期的状癌.
- 确定酒后驾驶对减少不确定的TRG得分和增加放射科医生的信心的影响.
主要方法:
- 对85名状癌患者的回顾性分析,这些患者在化疗放射治疗前和后3个月内接受了MRI.
- 四名放射科医生独立得分T2加权MRI,然后使用5点TRG系统DWI组合T2加权MRI.
- 评分信任度和观察者间的共识得到了评估.
主要成果:
- 添加DWI将不确定的TRG-3分数的比例从24%降至12% (p < 0.001).
- 不确定的分数最常被转换为一个优秀的反应 (DWI-TRG-2).
- 放射科医生得分的信心在DWI (p < 0.001) 中显著增加.
结论:
- 扩散加权成像补充了T2加权的MRI,以改善瘤响应评估在状癌.
- DWI有效地降低了不确定的TRG得分,并提高了放射科医生对早期治疗后评估的信心.
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