Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Bridging tumor biology and radiomics through an ultra-large physics-driven vascular model.

npj biomedical innovations·2026
Same author

Hydrogen evolution and dynamics in hydrogel electrochemical cells for ischemia-reperfusion therapy.

Nature chemical engineering·2026
Same author

Ultrasound characteristics vs. outdoor activities impacts on obese adolescents: a cross-sectional cardiopulmonary study.

Nutrition & metabolism·2026
Same author

Spherical radiomics for radiogenomic assessment of glioblastoma heterogeneity.

Neuro-oncology advances·2026
Same author

Factors affecting loneliness in pregnant women: A scoping review.

BMC pregnancy and childbirth·2026
Same author

Programming touch-me-not knot topologies for rapid and diverse leaping and flying motions.

Science (New York, N.Y.)·2026

相关实验视频

Updated: Jul 23, 2025

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis
11:29

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Published on: December 18, 2014

12.0K

盖尔:用于大型多细胞系统的GPU驱动的3D混合模拟器.

Jiayi Du1, Yu Zhou2, Lihua Jin2

  • 1Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, California, United States of America.

PloS one
|July 18, 2023
PubMed
概括

我们开发了Gell,这是一个基于GPU的平台,用于大规模的混合计算建模. 盖尔在个人电脑上将多细胞系统的模拟加速了150倍,使复杂的生物建模更容易获得.

更多相关视频

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System
09:56

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

1.7K
Hydrogel Arrays Enable Increased Throughput for Screening Effects of Matrix Components and Therapeutics in 3D Tumor Models
10:49

Hydrogel Arrays Enable Increased Throughput for Screening Effects of Matrix Components and Therapeutics in 3D Tumor Models

Published on: June 16, 2022

2.6K

相关实验视频

Last Updated: Jul 23, 2025

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis
11:29

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Published on: December 18, 2014

12.0K
Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System
09:56

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

1.7K
Hydrogel Arrays Enable Increased Throughput for Screening Effects of Matrix Components and Therapeutics in 3D Tumor Models
10:49

Hydrogel Arrays Enable Increased Throughput for Screening Effects of Matrix Components and Therapeutics in 3D Tumor Models

Published on: June 16, 2022

2.6K

科学领域:

  • 计算生物学 计算生物学
  • 生物物理学的生物物理.
  • 系统生物学 系统生物学

背景情况:

  • 混合计算模型模拟多细胞动态,但面临大规模系统的计算成本限制.
  • 生物系统的复杂性不断增加,需要对可访问的硬件提供高效的模拟方法.

研究的目的:

  • 开发一个基于GPU的快速和内存高效的平台,Gell (GPU Cell),用于大规模的混合计算建模.
  • 在标准计算设备上实现复杂的多细胞系统模拟.

主要方法:

  • 开发了Gell,这是一个开源的GPU加速混合计算建模平台.
  • 在GPU上实现完全并行,以提高计算效率.
  • 引入了一种新的voxel排序方法,以优化细胞-细胞机械相互作用建模.

主要成果:

  • 盖尔在个人电脑上高效地模拟了数以千万计细胞的系统.
  • 与最新的基于CPU的模拟器相比,演示了~150X的加速.
  • 与基于CPU的方法相比,实现了十分之一的内存需求.

结论:

  • 格尔显著降低了大规模混合模拟的计算成本.
  • 该平台促进了复杂的多细胞系统的先进研究,包括疾病建模,如管道癌 in situ (DCIS).
  • 盖尔民主化了对强大的计算生物学工具的访问.