在移植失败后进行腹腔透析:在移植前比较患有和没有pd的患者
Na Tian1, Han Meng1, Winston W S Fung2
1Department of Nephrology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia.
PloS one
|July 18, 2023
概括
在移植失败后接受腹膜透析 (PD) 的患者表现与新PD患者相似. 然而,那些以前有PD病史的人在回归到PD移植后失败时经历了变化的腹运输.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 脏替代疗法治疗 脏替代疗法
- 移植 移植 移植 移植
背景情况:
- 围透析 (PD) 在代移植失败后的临床结果也在讨论中.
- 关于在移植前使用PD并在全移植损失后恢复PD的患者的数据有限.
研究的目的:
- 为了比较在代移植失败后患有PD的患者的临床结果,与新患PD患者的对照组进行比较.
- 为了研究之前使用的PD在移植之前对allograft失败后的结果的影响.
主要方法:
- 在2001年至2020年期间,对100名患者进行了回顾性审查,这些患者在移植后发生了PD (移植失败组) 失败 (移植失败组).
- 与200名年龄,性别和糖尿病匹配的新PD患者 (对照组) 的临床结果进行比较.
- 根据先前的PD病史,在失败的移植组内的子组分析.
主要成果:
- 在移植失败和对照组之间,患者2年生存率 (83.3%与87.8%) 或技术生存率 (66.5%与71.7%) 没有显著差异.
- 在两组中观察到类似的住院和腹膜炎率.
- 以前患有PD病史并恢复PD移植后失败的患者表现出腹运输 (D/P4和MTAC肌素) 的增加.
结论:
- 腹腔透析为脏移植失败的患者和新PD患者提供了可比的临床结果.
- 移植前的PD病史,然后在异位移植失败后恢复到PD,与增高的腹膜运输参数有关.
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