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Updated: Jul 23, 2025

Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
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Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins

Published on: October 18, 2022

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为可扩展和多输入的CRISPRa/i电路设计可激活的促进器.

Diego Alba Burbano1,2, Ryan A L Cardiff2,3, Benjamin I Tickman2,3

  • 1Department of Chemical Engineering, University of Washington, Seattle, WA 98195.

Proceedings of the National Academy of Sciences of the United States of America
|July 18, 2023
PubMed
概括

科学家们使用CRISPR技术设计了高性能可激活促进体,用于构建复杂的基因调节网络 (GRNs). 这一突破使得在无细胞系统中具有精确控制的更深更宽的合成GRNs成为可能.

关键词:
在CRISPR中激活CRISPR.可激活的促进器工程.没有细胞的细胞.基因监管网络 基因监管网络基因电路是基因电路.

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