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Updated: Jul 23, 2025

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
07:24

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

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希斯甲基转移酶NSD2激活PKCα以驱动多发性髓瘤中的代谢重编程和莱纳利多米德耐药性

Phyllis S Y Chong1,2, Jing-Yuan Chooi1, Julia S L Lim1,2

  • 1Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Cancer research
|July 18, 2023
PubMed
概括

这项研究揭示了蛋白质激酶Cαα (PKCα) 通过上调糖分解来驱动多发性骨髓瘤中的代谢重编程. 这种表观遗传-代谢联系提供了治疗点,并将乳酸确定为免疫调节药物的不良反应的生物标志物.

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