与C型肝炎相关住院病例的时间趋势,美国,2000-2019年
Megan G Hofmeister1, Yuna Zhong1, Anne C Moorman1
1Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia.
概括
2013年以后,C型肝炎病毒 (HCV) 住院病例随着直接作用抗病毒 (DAA) 的可用性而减少. 然而,随着人口结构的变化,下降有所不同,这凸显了需要公平的DAA接入来消除HCV作为公共卫生威胁的需要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 肝炎C病毒 (HCV) 感染带来了严重的住院负担.
- 了解HCV住院病例的时间趋势至关重要,尤其是在直接作用抗病毒疗法 (DAA) 出现之后.
研究的目的:
- 描述与HCV相关的住院率的时间趋势.
- 在DAA引入之前和之后分析这些趋势.
主要方法:
- 利用了来自全国住院患者样本 (2000-2019) 的数据,针对18岁及以上的成年人.
- 基于初级或二级诊断,定义了与HCV相关的住院病例.
- 分析了国家特征和年龄调整后的住院率.
主要成果:
- 在2000年至2019年期间,估计有1,286,397例与HCV相关的住院病例发生.
- 根据年龄调整的住院率在2012年达到峰值,到2019年下降,在特定年龄组 (55-64岁),医疗补助受益者和黑人非西班牙裔个人中观察到显著增加.
- 住院病例最常见的是45-64岁的个人,男性,白人非西班牙裔人士以及医疗补助/医疗保险的人.
结论:
- 2013年后,HCV住院率下降,这与DAA的可用性相吻合.
- 这些下降的差异在年龄,种族/族裔和保险类别中被注意到.
- 扩大DAA治疗的机会,特别是对医疗补助/医疗保险的受益者来说,对于减少差距和努力消除HCV至关重要.
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