癌症患者的30天非计划性医院再入院和健康社会决定因素的影响:一种机器学习方法
Nickolas Stabellini1,2,3,4, Aziz Nazha5, Nikita Agrawal6
1Graduate Education Office, Case Western Reserve University School of Medicine, Cleveland, OH.
JCO clinical cancer informatics
|July 18, 2023
概括
机器学习准确地预测了癌症患者的30天计划外的医院再入院情况. 关键因素包括先前的再入院,并发症和健康的社会决定因素 (SDOH).
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 机器学习 机器学习
背景情况:
- 在癌症护理中,无计划的再入院是癌症护理的一个重大挑战.
- 识别高风险再接收的患者对于资源分配和患者的治疗结果至关重要.
研究的目的:
- 开发和验证一种特定于癌症的机器学习 (ML) 模型,用于预测固体瘤患者的30天无计划再入院.
- 确定与再接收风险相关的关键临床和社会健康决定因素 (SDOH) 因素.
主要方法:
- 分析了两个成年患有固体瘤的患者队列:一个有详细的SDOH数据,一个没有详细的SDOH数据.
- 基于树的ML模型经过训练,验证,并使用时间分区数据进行测试 (70%的训练,20%的验证,10%的测试).
- 模型性能使用包括ROC,AUC,精度,回忆和准确性在内的指标进行评估.
主要成果:
- 在包括的13,717名患者中,有21.3%的患者在30天内重新入院.
- 最重要的非SDOH预测因素包括以前的再入院,并发病率得分和入院类型.
- 关键的SDOH预测指标包括社区犯罪,收入和财富指数.
结论:
- 一个针对癌症的ML模型可以准确地识别高风险的患者无计划的医院再入院.
- 临床因素和SDOH都是癌症患者再接收风险的关键驱动因素.
- 整合SDOH数据增强了ML模型对癌症患者再入院的预测能力.
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