关于阿托皮性湿疹复制 (RECAP) 调查问卷的有效性,可靠性,响应性和解释性
Junfen Zhang1, Aviël Ragamin2, Geertruida L E Romeijn1
1Department of Dermatology, University of Groningen, University Medical Center Groningen, the Netherlands.
The British journal of dermatology
|July 18, 2023
概括
复杂性湿疹复制 (RECAP) 调查问卷显示,对于患有无性皮肤炎 (AD) 的成年人来说,其有效性很好,可靠性很好. 这项研究为RECAP分数提供了可解释性指南,有助于临床实践和研究.
科学领域:
- 皮肤病学 皮肤病学
- 临床测量 临床测量
- 心理测量 心理测量 心理测量
背景情况:
- 有限的研究存在于阿托皮性湿疹 (RECAP) 问卷的测量特性,特别是在解释性方面.
- 亚托皮炎 (AD) 管理需要经过验证的工具来评估疾病控制和治疗的有效性.
研究的目的:
- 评估RECAP调查问卷的荷兰版本在患有AD的成年人中的有效性,可靠性,响应性和可解释性.
- 建立RECAP分数的解释性标准,包括疾病控制和临床重要变化的门.
主要方法:
- 一项前性研究,涉及200名患有AD的成年人,完成RECAP,参考仪器,并在基线和后续 (短期和长期) 进行定问题.
- 使用假设测试来评估有效性和响应性. 使用标准测量误差 (SEMagreement) 和类内相关系数 (ICCagreement) 来确定可靠性.
- 通过提出湿疹控制带来解释性,并通过使用基方法确定最小可检测变化 (SDC) 和最小重要的变化 (MIC).
主要成果:
- 该RECAP表现出良好的单一评分有效性 (82%的假设得到证实) 和出色的可靠性 (ICCagreement = 0.988).
- 反应程度中等 (59%的假设得到证实). 已知组分析显示,基于疾病严重程度和生活质量受损的RECAP得分存在显著差异.
- 可解释性发现包括用于湿疹控制的建议波段,对于"不受控制"的AD的截止分数≥6,SDC为3.2分,MIC为3.9分.
结论:
- 荷兰RECAP问卷是一个有效,可靠和适度响应的工具,用于评估成年人的亚托皮炎.
- 该研究提供了关键的可解释性数据,表明识别不受控制的AD的值≥6和临床重要改善的MIC≥4.
- 这些发现支持将RECAP纳入常规临床实践和研究,与国际建议保持一致.
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