Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.8K
Phylogenetic Trees03:21

Phylogenetic Trees

45.6K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
45.6K
Phylogeny01:23

Phylogeny

44.6K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
44.6K
Survival Tree01:19

Survival Tree

115
Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
 Building a Survival Tree
Constructing a...
115
Speciation Rates01:07

Speciation Rates

21.3K
Overview
21.3K
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

578
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
578

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The Origin of Life in the Light of Evolution.

ArXiv·2026
Same author

The prokaryotic origins of the COMMD protein family involved in eukaryotic membrane trafficking.

Nature communications·2026
Same author

Signatures of gene transfer in the parallel evolution of osmotrophic specialization in eukaryotes.

Nature ecology & evolution·2026
Same author

New lineages provide insights into the convergent evolution of extreme salt adaptation within symbiotic Archaea.

Molecular biology and evolution·2026
Same author

Author Correction: Unbinned contigs expand known diversity in the global microbiome.

Nature microbiology·2026
Same author

Phylogenomic mixture models outperform homogeneous and partitioned models.

Molecular biology and evolution·2026
Same journal

Genomic evidence for natural selection underlying high-altitude adaptive hemoglobin levels among Peruvian Andeans.

Genome biology and evolution·2026
Same journal

Host Range Breadth Correlates with Genic Diversity in Honeybee Phages.

Genome biology and evolution·2026
Same journal

Genome-wide analysis of an endangered axolotl endemic to Mexico reveals genomic variation associated with body condition, environment and infection by a pathogenic fungus.

Genome biology and evolution·2026
Same journal

Conservation of IAMT preference for indole acetic acid methylation across 250 million years of seed plant divergence, with only one recent evolutionary switch in Ocimum.

Genome biology and evolution·2026
Same journal

Regulatory logic and transposable element dynamics in Caenorhabditis genomes.

Genome biology and evolution·2026
Same journal

Interchromosomal translocations and large deletions drive the evolution of the outlier chromosome in the smallest photosynthetic eukaryote.

Genome biology and evolution·2026
查看所有相关文章

相关实验视频

Updated: Jul 23, 2025

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
04:35

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

3.4K

使用ALE和GeneRax进行参数估计和物种树根植.

Tom A Williams1, Adrián A Davín2, Benoit Morel3,4

  • 1School of Biological Sciences, University of Bristol, 24 Tyndall Ave, Bristol BS8 1TH, United Kingdom.

Genome biology and evolution
|July 18, 2023
PubMed
概括
此摘要是机器生成的。

基因树-物种树和解工具,如ALE和GeneRax准确地推断基因进化事件和根物种树. 尽管最近有批评,但这些方法对于研究各种生命形式的基因组进化是可靠的.

关键词:
进行比较的基因组学.基因树物种树和解 基因树物种树和解微生物进化过程中的微生物.人类遗传学 遗传学

更多相关视频

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

16.0K
A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.4K

相关实验视频

Last Updated: Jul 23, 2025

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
04:35

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

3.4K
Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

16.0K
A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.4K

科学领域:

  • 人类遗传学 是一个学科.
  • 计算生物学 计算生物学
  • 进化基因组学 进化基因组学

背景情况:

  • 可能性基因树-物种树和解方法,包括ALE和GeneRax,用于推断基因重复,转移和丢失事件.
  • 这些方法是绘制基因家族起源和植根物种树木的基础,先前在古生物,细菌和真核生物中应用过.
  • 最近的担忧是质疑基于ALE/GeneRax模型的重复和转移事件估计的可靠性,这可能会影响物种树的根植.

研究的目的:

  • 严格评估关于ALE/GeneRax调和方法准确性的批评.
  • 验证这些工具用于推断基因复制,转移和丢失事件的可靠性.
  • 评估这些方法对物种树木根植在不同生命领域的影响.

主要方法:

  • 利用模拟数据集在受控条件下测试ALE/GeneRax的准确性.
  • 将ALE/GeneRax结果与使用经验生物数据的替代方法方法进行比较.
  • 分析了基因复制和转移频率跨越各种血统,以评估生物的一致性.

主要成果:

  • ALE和GeneRax在模拟数据上证明了准确性.
  • 在经验数据上,ALE/GeneRax的结果与替代方法有很好的一致性.
  • ALE成功地捕获了基因复制和跨系基因转移率的生物学相关变异.
  • 在植物和opisthokonts.onts.中,ALE始终恢复了已建立的物种树根.
  • 在细菌中,ALE的根预测与不确定性区域的其他方法保持一致.

结论:

  • ALE/GeneRax模型和基于和解的方法被验证为研究基因组进化的准确工具.
  • 这些方法可靠地推断出基因复制,转移和损失事件,并有助于物种树根植.
  • ALE恢复生物学上一致的模式的能力加强了它在进化基因组学研究中的实用性.