在多个系统缩的睡眠期间面部紧张:不仅仅是一个坏梦
Lecca Rosamaria1,2, Figorilli Michela2, Bouniol Emma1
1Sleep and EEG, Neurophysiology Unit, Neurology Department, CHU University Hospital and UMR 6602-Université Clermont Auvergne, CNRS, Institute Pascal, Clermont-Ferrand, France.
Sleep
|July 18, 2023
概括
睡眠期间的面部运动,特别是"面部紧张",在多系统缩 (MSA) 中比在帕金森病 (PD) 中更常见. 这可能表明由于MSA患者的神经退行症的睡眠状态分离.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 神经科学是一个神经科学.
背景情况:
- 帕金森病 (PD) 和多个系统缩 (MSA) 可以导致睡眠障碍.
- 睡眠状态分离是这些神经退行性疾病的一个潜在问题.
- 在MSA患者中,在睡眠期间注意到明显的面部运动.
研究的目的:
- 为了比较MSA患者与PD患者和对照患者在睡眠期间的面部运动活动和下巴肌肉度.
- 为了调查是否特定的面部运动或肌肉度变化在睡眠期间特征MSA.
主要方法:
- 视频多睡眠图和下巴电肌图用于分析62名参与者的睡眠 (11 MSA,38 PD,13对照).
- 面部运动被分类,下巴肌肉缩指数在REM和NREM睡眠期间计算.
- 分析是由一个睡眠专家对患者病理和睡眠阶段进行的.
主要成果:
- 与对照组相比,MSA患者在NREM睡眠期间表现出更多的面部运动.
- "疲劳的脸"在MSA中比PD更频繁,即使考虑到REM睡眠行为障碍 (RBD).
- 与对照组和PD相比,MSA患者在REM和NREM睡眠期间表现出较低的动指数,在RBD调整后,与PD相比,NREM阶段N1和N2仍然存在显著差异.
结论:
- 增加的面部运动,特别是"面部紧张",是MSA在睡眠期间的特征.
- 在MSA中肌肉度和面部活动升高可能意味着睡眠状态分离.
- 这些发现表明,在出现这些与睡眠相关的运动现象的MSA患者中,神经退行更严重.
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