在TECLISTAMAB-ASSOCIATED SCLEROUVEITIS中,出现了低血压的情况.
Tianyu Liu1, Turner Schwartz1, Apoorv P Chebolu1
1Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania; and.
Retinal cases & brief reports
|July 18, 2023
概括
新的多发性骨髓瘤治疗方法Teclistamab可能会导致带有hypopyon的硬化性脊髓炎. 用类固醇及时治疗和药物中断改善了患者的症状.
科学领域:
- 眼科医生 眼科 眼科
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 多发性骨髓瘤是一种血液性恶性瘤.
- 德克利斯塔马布是一种用于复发性或耐火性多发性髓瘤的双特异性抗体.
- 眼部不良事件是新型癌症疗法的一个问题.
研究的目的:
- 为了描述一种带有hypopyon的硬化症病例.
- 调查特克利斯塔马布与这种眼睛疾病之间的潜在关联.
主要方法:
- 案例报告. 情况报告.
- 临床表现和诊断工作.
- 纳兰乔药物不良反应概率尺度评估.
主要成果:
- 一名患有多发性骨髓瘤的患者在开始服用teclistamab后一周就出现了带有hypopyon的硬化炎.
- 负面的文化排除了传染病的原因.
- 随着局部类固醇和暂时停止使用teclistamab,症状有所改善,这表明可能与药物有关.
结论:
- 德克利斯塔马布可能与硬化性脊髓炎和hypopyon有关.
- 眼科医生和瘤学家应该意识到这种潜在的不良影响.
- 需要进一步的研究来证实这种关联并阐明机制.
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