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Updated: Jul 23, 2025

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
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下一代泛癌血液蛋白质组分析,使用近距离延伸试验

María Bueno Álvez1, Fredrik Edfors1, Kalle von Feilitzen1

  • 1Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology, Stockholm, Sweden.

Nature communications
|July 18, 2023
PubMed
概括

这项研究分析了1400多名癌症患者的血液蛋白质,确定了癌症早期诊断和个性化治疗的关键蛋白质签名. "疾病血液图谱"为癌症研究提供了宝贵的资源.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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