核磁共振成像功能可以预测前列腺癌骨转移的类型
Hiroaki Koyama1, Ryo Kurokawa2, Shimpei Kato1
1Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Scientific reports
|July 18, 2023
概括
前列腺癌的骨转移可以是骨质可塑性或非骨质可塑性. 在MRI上高正常化的T2信号强度 (nT2SI) 和PSA密度可能预测非骨质细胞骨转移,需要进一步检查.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 病理学 病理学 病理学
背景情况:
- 前列腺癌 (PCa) 中的骨转移 (BMs) 通常是骨质质的,但存在骨解或混合类型.
- 在患者管理中,区分骨质可塑性和非骨质可塑性骨髓瘤是至关重要的.
研究的目的:
- 调查前列腺MRI和骨质疏松性和非骨质疏松性骨髓瘤患者之间的临床发现的差异.
- 为了确定非骨质细胞骨髓瘤的预测因素.
主要方法:
- 具有病理证明的BM的PCa患者的回顾性研究 (2014-2021年).
- 临床数据 (年龄,格里森得分,PSA密度) 和MRI发现 (平均ADC,nT2SI,PI-RADS类别) 的比较.
- 多变量逻辑回归分析,以确定非骨质细胞骨髓瘤的独立预测因子.
主要成果:
- 25名患者患有骨质可塑性骨髓瘤,7名患者患有非骨质可塑性骨髓瘤.
- 非骨质细胞组显示出明显更高的PSA密度和正常化的T2信号强度 (nT2SI).
- nT2SI成为非骨质细胞骨髓瘤的独立预测因子.
结论:
- 在PCa患者中,高的nT2SI和PSA密度可能表明非骨质可塑性骨转移的可能性更高.
- 这些发现表明,需要在具有这些MRI特征的患者中更仔细地检查骨解性BMs.
相关概念视频
01:27Imaging Studies IV: Magnetic Resonance Imaging
29
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
29
01:24Magnetic Resonance Imaging
5.2K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.2K