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Updated: Jul 23, 2025

Using Human Induced Pluripotent Stem Cell-derived Intestinal Organoids to Study and Modify Epithelial Cell Protection Against Salmonella and Other Pathogens
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Published on: May 12, 2019

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有效的SARS-CoV-2复制肠上皮细胞单层,从人类诱导的多能干细胞中分化出来

Shohei Minami1, Naomi Matsumoto1, Hiroko Omori2

  • 1Department of Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, 565-0871, Japan.

Scientific reports
|July 18, 2023
PubMed
概括

人类诱导的多能干细胞衍生肠上皮细胞 (IEC) 单层为研究SARS-CoV-2提供了一个新的工具. 这些细胞支持有效的病毒复制,TMPRSS2抑制阻断感染,验证了它们在研究中的使用.

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