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Updated: Jul 23, 2025

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RUFY3 调节了内酶体的周核定位,抗原呈现和活化细胞中的迁移

Rémy Char1, Zhuangzhuang Liu2, Cédric Jacqueline3

  • 1Aix Marseille Université, CNRS, INSERM, CIML, 13288, Marseille, cedex 9, France.

Nature communications
|July 18, 2023
PubMed
概括

含有RUN和FYVE域的蛋白3 (RUFY3) 异形iRUFY3对免疫细胞功能至关重要. 它调节了内溶酶体定位,巨细胞迁移和免疫反应,影响宿主对病原体的防御.

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