在接受腹手术的患者中,二次性甲状腺功能障碍症 (SHPT) 的患病率和危险因素
Laura E Fischer1,2, Fernando Moreno-Garcia3, Rachel Tran3
1Department of Surgery, University of Oklahoma, Oklahoma City, USA. laura-fischer@ouhsc.edu.
Surgical endoscopy
|July 18, 2023
概括
二次性偏甲状腺症 (SHPT) 在减肥手术后很常见,影响超过70%的患者. 尽管服用维生素补充剂,许多病例仍然存在,这表明需要改进治疗策略.
科学领域:
- 内分泌学 在内分泌学.
- 代谢手术 代谢手术
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 二次性偏甲状腺症 (SHPT) 存在骨质疏松和骨折的风险.
- 了解SHPT患病率和风险因素对于管理这一群体的骨健康至关重要.
研究的目的:
- 为了确定接受减肥手术的患者中SHPT的患病率.
- 在这个队列中确定与SHPT相关的风险因素.
主要方法:
- 350名减肥手术患者的回顾性图表审查.
- 在多个时间点收集人口统计,临床和生化数据 (甲状腺激素,,维生素D3).
- 统计分析包括千平方,曼-惠特尼U和后勤回归.
主要成果:
- 在任何时间点,SHPT患病率达到72.9%.
- 42.4%的患者在1年内患有持续性SHPT,即使服用补充剂.
- 基线SHPT与黑人种族和T2DM相关;1年的SHPT与RYGB,抑郁症和更长的节目持续时间相关.
结论:
- SHPT是非常普遍的腹腔外科后手术,具有显著的持续性.
- 目前的维生素D3和协议可能不足.
- 需要进一步的研究,以制定有效的SHPT管理策略,在后腹患者.
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