相关实验视频
Updated: Jul 23, 2025

09:22
Bead Based Multiplex Assay for Analysis of Tear Cytokine Profiles
Published on: October 13, 2017
11.9K
眼睛手术后眼中的液和补充激活产品
Hiroki Maehara1, Koki Norikawa1, Keiichiro Tanaka1
1Department of Ophthalmology, Fukushima Medical University School of Medicine, Hikarigaoka 1, Fukushima, 960-1247, Japan.
BMC ophthalmology
|July 18, 2023
概括
视膜切除和白内障手术后显著增加了膜补充激活产品 (CAPs). 预先存在的干眼可能会延长炎症并延迟这些手术后的眼睛表面恢复.
科学领域:
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
- 手术科学 手术科学
背景情况:
- 尽管白内障手术的侵入性降低了,但它仍然会导致术后炎症和干眼综合征.
- 天生的免疫系统,特别是补充激活,可能在眼睛炎症和手术后的愈合中发挥作用.
研究的目的:
- 为了研究结合玻璃切除和白内障手术后膜补充激活产品 (CAPs) 和眼睛表面的变化.
- 探索手术前水分和手术后炎症之间的关系.
主要方法:
- 一项针对43名患者进行的前性研究,这些患者接受了化和玻璃切除术.
- 施尔默测试 (ST) 和撕裂CAP (C3a,C4a,C5a) 在基线,4日和手术后1个月的测量.
- 使用细胞计数珠阵列和与ST值的相关性分析CAPs.
主要成果:
- 眼CAPs (C3a,C4a,C5a) 在手术后4天显著增加,并在手术后1个月保持升高.
- 施尔默测试显示,在4天后的短暂增加,在1个月后恢复到接近基线.
- 手术前较低ST (干眼) 的患者在手术后1个月表现出明显更高的C3a水平.
结论:
- 结合玻璃切除术和白内障手术导致眼膜补充剂激活的增加.
- 手术前的眼分泌缺陷可能与延长的补体激活和延迟的眼睛表面恢复有关.
相关概念视频
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
5.1K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
5.1K
Complement System
2.4K
The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a...
2.4K
Accessory Structures of the Eye
1.6K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.6K
Glaucoma: Overview
623
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
623
Angle Closure Glaucoma: Treatment
572
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
572

