经过治疗的牙周炎和第一次心肌梗塞后的复发事件:丹麦全国性队列研究
Andrea Kjellström Wagner1, Maria D'Souza1, Casper N Bang2
1Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark.
Journal of clinical periodontology
|July 19, 2023
概括
之前的牙周治疗没有改变心肌梗塞 (MI) 后的复发性心血管事件. 然而,没有先前的牙科诊所显著增加了主要不良心血管事件 (MACE) 和相关结果的风险.
科学领域:
- 心血管医学 心血管医学
- 牙周病学 牙周病学
- 公共卫生 公共卫生
背景情况:
- 牙周病是一种与全身性疾病相关的慢性炎症状况.
- 心肌梗塞 (MI) 幸存者面临心血管事件复发的风险.
- 牙周治疗与MI后结果之间的关联需要进一步研究.
研究的目的:
- 为了检查之前的牙周治疗和在第一次心脏病发作后复发的主要心血管不良事件 (MACE) 之间的关系.
- 为了确定口腔健康状况是否影响心血管事件在心脏病发作患者的复发.
主要方法:
- 一项全国范围的队列研究包括103,949名首次心脏病发作患者 (2000-2015年).
- 患者根据在心脏病发作前一年内获得的口腔健康护理进行了分类.
- 调整的几率比率 (ORs) 和95%的置信区间 (CI) 使用后勤回归计算,以评估3年MACE风险.
主要成果:
- 与牙周健康个体相比,经过治疗的牙周炎 (PD) 患者的3年MACE风险相似 (OR 0.97 [95% CI 0.92-1.03]).
- 没有先前去看牙的患者有更高的并发症和更高的调整后3年MACE风险 (OR1.47 [95%CI1.42-1.52]),心血管死亡 (OR1.71 [95%CI1.64-1.78]) 和心力衰竭 (OR1.13 [95%CI1.07-1.20)).
结论:
- 在心脏病发作前一年接受治疗的牙周病与复发性心血管事件无关.
- 在首次心脏病发作之前缺乏牙科检查,已成为心血管疾病复发的独立风险因素.
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