用于在人体皮肤体内生物力学表征的设备的定量比较
Håvar J Junker1, Bettina Thumm1, Sascha Halvachizadeh2
1Present address: Institute for Mechanical Systems, Department of Mechanical and Process Engineering, ETH Zurich, Leonhardstrasse 21, Zurich, 8092 Switzerland.
Mechanics of soft materials
|July 19, 2023
概括
这项研究比较了三种非侵入性皮肤表征装置:吸收,动态剪切和缩. 结果显示,这些方法以不同的方式测量皮肤硬性,影响临床研究的解释.
科学领域:
- 生物医学工程 生物医学工程
- 皮肤病学 皮肤病学
- 材料科学 材料科学 材料科学
背景情况:
- 非侵入性皮肤表征对于临床研究至关重要.
- 有许多技术可以测量皮肤的生物力学特性.
- 缺乏对常见方法的比较分析.
研究的目的:
- 描述和比较三种常见的皮肤生物力学测试原理:吸收,动态剪切负荷和缩.
- 评估它们在体内分辨皮肤特性的能力.
- 评估每个设备的可靠性.
主要方法:
- 使用了具有可调整机械性能的合成模型系统.
- 采用有限元模型进行结果合理化.
- 在身体不同部位的健康志愿者身上进行了体内测量.
主要成果:
- 三个分析的功能原理不同地感知人类皮肤的性.
- 在体内测量表明在皮肤生物力学差异化方面具有不同的能力.
- 在设备中,评价器内和评价器间的可靠性各不相同.
结论:
- 选择非侵入性皮肤表征装置会影响测量结果.
- 了解这些差异对于准确解释皮肤生物力学数据至关重要.
- 需要进一步的研究来标准化临床皮肤研究的方法.
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