Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Development of Immunocompetence01:22

Development of Immunocompetence

351
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
351
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin01:26

Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin

708
Directly acting muscle relaxants like dantrolene and botulinum toxin (BoNT) have distinct mechanisms and applications. Dantrolene, a hydantoin derivative, acts on the ryanodine receptor (RYR1) in skeletal muscle cells. RYR1 are calcium channels present at the sarcoplasmic reticulum membrane. In response to excitation, they release calcium ions from the sarcoplasmic reticulum to the cytosol. Calcium promotes actin-myosin-mediated contraction of muscles.
The binding of dantrolene to the RYR1...
708

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Tales from the 2SLGBTQ+ family medicine community and supporters.

Canadian family physician Medecin de famille canadien·2026
Same author

Expert Validation of an Artificial Intelligence-Enabled Trial Matching Solution Using Real-World Data From Patients With Cancer.

JCO oncology practice·2026
Same author

Lack of online price transparency of small animal veterinary clinics in the United States.

Frontiers in veterinary science·2026
Same author

De-Escalated Adjuvant Radiation Therapy in Patients With HPV-Positive Oropharyngeal Cancer.

JAMA network open·2026
Same author

Curriculum Resources for Integrating Respectful Maternity Care Into Health Professions Education: A Rapid Scoping Review.

Journal of midwifery & women's health·2026
Same author

Episiotomy and Obstetric Anal Sphincter Injury Among Unassisted Vaginal Births: A Retrospective Cohort Study.

The Australian & New Zealand journal of obstetrics & gynaecology·2026

相关实验视频

Updated: Jul 23, 2025

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
12:25

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays

Published on: March 3, 2014

16.0K

婴儿肉毒症 在婴儿肉毒症.

Victoria Morris1, Robert Wians1, Jessica Wilson1

  • 1McGovern Medical School at the University of Texas Health Science Center, Department of Emergency Medicine, Houston, TX.

Journal of education & teaching in emergency medicine
|July 19, 2023
PubMed
概括
此摘要是机器生成的。

婴儿肉毒症是婴儿低血压和呼吸衰竭的罕见原因,需要及时识别和给予抗毒素. 这种模拟提高了居民和同事的准备能力,以管理这种危急的情况.

更多相关视频

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
10:30

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators

Published on: December 27, 2013

5.4K
Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

19.6K

相关实验视频

Last Updated: Jul 23, 2025

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
12:25

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays

Published on: March 3, 2014

16.0K
A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
10:30

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators

Published on: December 27, 2013

5.4K
Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

19.6K

科学领域:

  • 儿科急救医学 儿科急救医学
  • 毒理学 毒理学 毒理学

背景情况:

  • 婴儿肉毒是一种罕见的,严重的疾病,导致低血压,吐和呼吸衰竭.
  • 早期识别下降性和呼吸困扰对于预防不良结果至关重要.

研究的目的:

  • 评估模拟在准备急诊医学和儿科急诊医学 (PEM) 实习生管理婴儿肉毒的有效性.
  • 提高学习者诊断,管理和启动婴儿肉毒主义治疗的能力.

主要方法:

  • 一个涉及婴儿肉毒的高准确度模拟案例与急诊医疗住院医生和PEM研究员进行.
  • 学习者练习差异诊断,呼吸道管理,抗毒素动员和支持性护理.
  • 收集了反,使用一个5点的利克特比例问卷模拟后.

主要成果:

  • 模拟和汇报从参与者那里得到了大部分积极的反.
  • 大多数参与者强烈同意或同意模拟将改善他们在真实临床场景中的表现.

结论:

  • 基于模拟的培训是有效的改善居民和同事准备管理罕见的,高急性病例,如婴儿肉毒.
  • 这种方法提高了诊断技能,管理策略和处理关键儿科紧急情况的信心.