关于处方级联的研究:一个范围审查
Zhe Chen1,2,3,4,5, Zheng Liu1,2,3,4,6, Linan Zeng1,2,3,4
1Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China.
Frontiers in pharmacology
|July 19, 2023
概括
处方级联,其中一个药物级联.
科学领域:
- 药监和药物安全 药监和药物安全
- 临床药学研究 临床药学研究
- 老年人药理学 老年人药理学
背景情况:
- 处方级联,一个已知问题超过二十年,在全球展示各种各样的研究进展.
- 国际上关于处方级联的研究缺乏统一的方法,需要进行系统的评估.
- 本研究旨在评估当前关于处方布的原始研究的现状.
研究的目的:
- 系统地评估处方级流的全球研究状况.
- 确定研究缺口,并为未来的研究提供参考资料.
- 为改善临床实践的药物安全提供信息.
主要方法:
- 在3个英语和4个中文数据库中进行全面的文献搜索,直到2022年1月.
- 32项符合条件的研究的独立数据提取和描述性分析.
- 方法和研究结果的比较分析包括研究.
主要成果:
- 分析了32项涉及11个国家的700多万患者的研究.
- 研究主要集中在老年人群中,有49个确定的处方级联路线.
- 心血管系统和痴呆症是常见的,通常涉及通道阻塞剂.
结论:
- 处方级联正在获得国际关注,特别是在患有心血管和神经疾病的老年人中.
- 对儿童和孕妇等特殊群体缺乏综合性研究.
- 进一步的深入研究和有效的干预措施对于减少处方级联发病率至关重要.
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