大动脉假肢的血液动力学参数 - KRAK-AS注册分析
Małgorzata Pińska1,2, Danuta Sorysz3,4, Magdalena Frączek-Jucha1,2
1Department of Coronary Disease and Heart Failure, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
概括
大动脉置换后患者与假肢不匹配 (PPM) 是常见的,特别是在机械或生物门中. 过导管手术显示PPM的发生率明显较低,这表明某些患者的治疗结果更好.
科学领域:
- 心脏病学 心脏病学
- 心血管外科心血管外科
- 生物医学工程 生物医学工程
背景情况:
- 大动脉狭窄需要更换门,但患者假肢不匹配 (PPM) 可能导致不良结果.
- 预测和避免PPM至关重要,特别是对于体型较大的患者.
研究的目的:
- 在现实世界患者队列中确定不同类型的假体门中PPM的频率.
- 根据克拉科夫大动脉狭窄注册表中的门类型分析PPM发生情况.
主要方法:
- 克拉科夫大动脉狭窄症 (KRAK-AS) 登记册包括2016年7月至10月期间接受大动脉干预的229名患者.
- 对患者进行了手术前和后的评估,随访3年,重点关注心声图数据和假肢类型 (机械,生物,透气管).
主要成果:
- 至少中度的PPM (iEOA ≤0.85cm2/m2) 发生在40%的机械,33%的生物,只有10%的跨导管接收者 (p=0.0001).
- 在机械组的17.6%和生物组的4.3%观察到严重的PPM (iEOA<0.65cm2/m2),但在透导管组没有.
结论:
- 患者与假肢不匹配是术术上更换大动脉的常见并发症.
- 通过导管的大动脉植入证明了与外科选择相比,PPM的发病率明显较低.
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