毒素A型用于生殖骨神经疼痛:一个病例报告
Yan Tereshko1, Belgrado Enrico2, Lettieri Christian2
1Clinical Neurology Unit, Udine University Hospital, Udine, Italy.
Frontiers in neurology
|July 19, 2023
概括
生殖骨神经疼痛是一种罕见的疼痛状况,治疗可能具有挑战性. 毒素A型 (BoNT/A) 的皮下注射可以为患有不耐药性生殖骨神经疼痛的患者提供暂时的疼痛缓解.
科学领域:
- 神经学 神经学
- 疼痛医学 医学 疼痛医学
- 皮肤病学 皮肤病学
背景情况:
- 生殖骨神经疼痛是一种不常见的神经病痛障碍.
- 它经常表现为耐火性症状,耐标准治疗.
- 传统疗法可能包括口服药物和局部药物.
相关概念视频
01:26Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
708
Directly acting muscle relaxants like dantrolene and botulinum toxin (BoNT) have distinct mechanisms and applications. Dantrolene, a hydantoin derivative, acts on the ryanodine receptor (RYR1) in skeletal muscle cells. RYR1 are calcium channels present at the sarcoplasmic reticulum membrane. In response to excitation, they release calcium ions from the sarcoplasmic reticulum to the cytosol. Calcium promotes actin-myosin-mediated contraction of muscles.
The binding of dantrolene to the RYR1...
The binding of dantrolene to the RYR1...
708
01:24Local Anesthetics: Differential Sensitivity of Nerve Fibers
871
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
871