基于异的双受体结合聚合物 嵌入结合长度和内部分子电荷转移,用于高效的光热转换
Yu Wang1,2, Hongsen Wang1,2, Jinni Deng1,3
1Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China.
Macromolecular rapid communications
|July 19, 2023
概括
研究人员开发了新的结合聚合物,用于增强光热瘤治疗. 这些材料在将近红外光转化为用于癌症治疗的热量方面表现出高效率.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 生物医学工程 生物医学工程
背景情况:
- 光热瘤治疗 (PTT) 和光声成像 (PA) 提供非侵入性癌症治疗选择.
- 开发高光稳定性和强近红外 (NIR) 吸收的高效光热剂至关重要,但具有挑战性.
研究的目的:
- 为了合成和描述PTT的新型基于isoindigo的双受体结合聚合物 (CPs).
- 评估它们的光学,电化学和NIR光热转换特性.
主要方法:
- 用于合成的绿色和无毒的直接化聚合 (DArP) 方法.
- 光学,电化学和光热转换性能的表征.
- 纳米粒子 (NP) 的形成用于评估.
主要成果:
- 合成了三种基于异印的双受体CP (P-IIG-TPD,P-IIG-DPP,P-IIG-EDOT-BT).
- 由于分子设计,聚合物表现出增强的光热转换效率 (PCE).
- P-IIG-EDOT-BT和P-IIG-DPPNP显示了高的PCE,分别为62%和78%,具有强大的NIR吸收.
结论:
- 双受体结合聚合物显示出作为NIR光热转换材料的前景.
- 分子设计策略可以改善PCE用于瘤诊断和治疗.
- 这项工作指导了癌症治疗先进CP的发展.
相关概念视频
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