抑郁症,焦虑症,失眠和经期失调在压力fingolimod-treated妇女多发性硬化症
1Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid, Jordan.
International journal of psychiatry in medicine
|July 19, 2023
概括
在约旦,患有多发性硬化症 (MS) 的压力较大的女性表现出高的抑郁,焦虑和失眠率. 这些情况与经期障碍有关,凸显了对MS患者综合护理的需要.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 妇女健康 妇女健康
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经系统疾病,影响生活质量.
- 芬戈利莫德是MS的常见治疗方法,但其对女性特定健康问题的影响尚未得到充分研究.
- 压力是管理MS等慢性疾病的重要因素.
研究的目的:
- 为了确定抑郁症,焦虑症,失眠症和更年障碍症的患病率,应对压力,接受fingolimod治疗的MS妇女.
- 在这个患者群体中确定与这些疾病相关的相关性.
- 为更好的患者管理提供临床实践的信息.
主要方法:
- 在约旦,对129名女性多发性硬化患者进行了横截面研究.
- 使用了经过验证的尺度:PHQ-9用于抑郁症,GAD-7用于焦虑症,ISI-A用于失眠.
- 使用WaLIDD测量来评估淋病,评估疼痛和对日常活动的影响.
主要成果:
- 观察到患病率很高:严重抑郁症为55.8%,严重焦虑症为62.0%,严重失眠症为36.4%,严重经期障碍症为23.3%.
- 抑郁与经期不良相关;焦虑与止痛药使用和经期不良相关.
- 失眠与30岁以上的年龄有关; 经期障碍与慢性疾病,焦虑和失眠有关.
结论:
- 在约旦,患有多发性硬化症的压力严重的妇女表现出抑郁症,焦虑症,失眠症和更年障碍症的高症状负担.
- 识别特定的患者特征可以帮助风险分层.
- 需要进一步的纵向研究来确定这些相互关联的条件之间的因果关系.
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