一项随机临床试验,评估数字疗法,以提高帕金森病患者的步行功能
Jay L Alberts1,2, Ryan D Kaya2, Amanda L Penko1
1Department of Biomedical Engineering, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, USA.
Neurorehabilitation and neural repair
|July 19, 2023
概括
使用DART平台进行的数字双任务训练有效地改善了帕金森病患者的步态. 这种增强现实方法显示的结果与传统方法相比不逊色,增加了姿势不稳定性和步行功能障碍的可访问性.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 数字健康数字健康
背景情况:
- 姿势不稳定和步行功能障碍 (PIGD) 是帕金森病 (PD) 的一种主要症状,在双重任务时会恶化.
- 传统的双重任务训练 (DTT) 改善了步态,但资源密集.
- 双任务增强现实处理 (DART) 平台提供了一个数字化解决方案,以提高PIGD的DTT可访问性.
研究的目的:
- 为了比较DART平台与PD患者PIGD传统DTT的疗效.
- 测试DART干预将导致明显的步态改善的假设,与传统的DTT相比.
主要方法:
- 一个单盲随机对照试验涉及47名患有PIGD的PD参与者.
- 参与者在8周内进行了16次治疗,其中一组使用了DART平台 (Microsoft HoloLens2) 和另一组使用传统的DTT.
- 主要结局评估了临床PD症状和单任务和双任务步态生物力学.
主要成果:
- 无论是DART还是传统的DTT群体,都在步行速度,节奏和步骤长度方面表现出显著的改善.
- 在两组干预组中,临床PD症状测量保持稳定.
- 在大多数条件下,DART组的步行速度改善与传统DTT组相比并非劣.
结论:
- DART平台是一个可行的数字治疗方法,用于改善帕金森病患者的PIGD.
- 通过DART提供数字DTT展示了扩大对这种未充分利用的干预措施的获取潜力.
- 这项研究支持DART作为一种有效和可访问的方法来管理PD的步行功能障碍.
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