耳前隔膜缺陷与无补偿性心力衰竭相关的肺高血压:窗口设备关闭后的结果
Ahmed Deniwar1, Jason Hernandez1,2, Enrique O Aregullin1,2
1Betz Congenital Heart Center, Helen DeVos Children's Hospital of Spectrum Health Hospital, Grand Rapids, MI, USA.
Cardiology in the young
|July 19, 2023
概括
在心脏衰竭和肺动脉高血压的成年人中,心房隔膜缺陷的窗口关闭安全地改善了心脏功能和氧气水平,显示了持续的益处.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 肺高血压是什么意思 肺高血压
背景情况:
- 在成人中,心房隔膜缺陷 (ASD) 通常导致心力衰竭和肺动脉高血压 (PAH).
- 未经治疗的ASD可以在第四个十年引起症状性疾病,其中30-49%的人患有心力衰竭.
- 肺血压影响8-10%的自闭症患者,主要是女性.
研究的目的:
- 评估通过导管封闭的ASD关闭在患有无补偿心力衰竭和PAH的患者中的安全性和有效性.
- 为了评估手术后的功能和血液动力学改善.
主要方法:
- 在5名患有严重心力衰竭和PAH的成年女性患者身上进行了透气管嵌的ASD闭合.
- 患者有不可避免的外科风险.
- 通过氧和度的变化,6分钟步行测试,NYHA类和血液动力学参数的变化来评估结果.
主要成果:
- 在6分钟步行测试距离和氧气和后过程中观察到显著改善.
- 血液动力学参数,包括肺血管阻力和压力,显著改善.
- 所有患者都经历了右心室大小和功能的改善,具有更好的NYHA类. 没有出现与手术相关的并发症.
结论:
- 在非补偿性心力衰竭和PAH的成年人中,Fenestrated ASD关闭是可行的和安全的选择.
- 该程序导致持续的血液动力学和功能性改善,提供了可行的治疗选择.
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