接收甲状腺功能与急性缺血性中风的90天结果有关
Qinghua Feng1, Yunze Li1, Yuan Zhu1
1Department of Neurology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, 210029, China.
Neuro endocrinology letters
|July 19, 2023
概括
甲状腺功能测试,包括自由三氨酸 (FT3) 和甲状腺刺激激素 (TSH),可以预测急性缺血性中风后的结果. 入院时较低的FT3和较高的TSH水平与中风患者90天功能结果较差有关.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 内部医学 内部医学
背景情况:
- 甲状腺功能障碍在急性缺血性中风 (AIS) 患者中很常见.
- 在AIS中甲状腺功能测试的预后价值仍在争论中.
- 预后因素的早期识别对于管理AIS患者至关重要.
研究的目的:
- 研究甲状腺功能测试 (TSH,FT3,FT4) 在入院时和AIS患者90天功能结果之间的关联.
- 为了确定甲状腺功能是否可以作为中风预后的独立预测因素.
主要方法:
- 对2021年1月至7月期间入院的699名AIS患者的回顾性分析.
- 评估90天的功能结果,使用修改后的排名表 (mRS).
- 统计分析包括单变量,多变量逻辑回归,三位数和TSH,FT3和FT4水平的子组分析.
主要成果:
- 在AIS患者中,自由三甲状腺素 (FT3) 与90天的不良结果负相关.
- 甲状腺刺激激素 (TSH) 在调整混因素后,也被发现与90天的不良结果有负相关性.
- 较高的TSH和较低的FT3三位体与90天后不良结果的发病率增加有关.
结论:
- 入院时的FT3和TSH水平都是AIS患者90天功能结果的显著负面预测指标.
- 在入院时进行甲状腺功能评估,为AIS提供了有价值的独立预后信息.
- 这些发现强调了在中风治疗中监测甲状腺功能的重要性.
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