在腹腔镜胆囊切除术患者的术前与术内抗策略:一项随机双盲研究
Polyxeni Theodosopoulou1, Chryssoula Staikou, Argyro Fassoulaki
1From the Department of Anaesthesia, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece (PT, CS, AF).
European journal of anaesthesiology
|July 19, 2023
概括
这项研究发现,当在手术前1小时或手术结束前给予丹塞时,预防手术后恶心和吐 (PONV) 没有显著差异. 对于Ondansetron,这两种计时策略在PONV预防方面同样有效.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
- 手术护理 手术护理
背景情况:
- 翁丹塞特朗是治疗术后恶心和吐 (PONV) 的有效药物.
- 与手术相比,丹塞特朗的最佳时间尚不清楚.
研究的目的:
- 为了比较外科手术前与外科手术内对PONV预防的丹塞的使用.
- 评估丹塞定时对PONV发病率的影响.
主要方法:
- 随机,双盲,单中心试验.
- 121名患者接受了腹腔镜胆囊切除术.
- 组接受了ondansetron在麻醉前1小时或手术结束前30分钟.
主要成果:
- 两组之间24小时后PONV发病率没有显著差异 (1.7%对5.3%,P=0.31).
- 恶心,吐和吐组合没有显著差异 (5.3%与10.5%,P=0.30).
- 术后疼痛强度没有差异.
结论:
- 在手术前和手术内给予丹塞,在预防PONV方面表现出相似的疗效.
- 目前的研究设计表明,对于PONV来说,一个时间对另一个时间没有好处.
相关概念视频
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
119
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
119
01:27Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
249
5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
249
01:28Cardiomyopathy VII: Pre and Post Operative Nursing Management
16
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
16