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通过初级阿尔多斯特罗尼斯的前体方法取副腎静脉样本:一个多中心研究
Hui Dong1, Jiangnan Huang2, Ying Zhang3
1Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
采用前阴方法的上腺静脉采样 (AVS) 对于初级阿尔多斯特症的诊断是安全有效的. 这种方法的成功率很高,为传统的股骨静脉接入提供了可行的替代方案.
科学领域:
- 内分泌学 在内分泌学.
- 干预性放射学 干预性放射学
- 血管外科 血管外科
背景情况:
- 上腺静脉采样 (AVS) 是区分原发性阿尔多斯顿主义亚型的黄金标准.
- 目前的AVS手术主要利用大腿静脉接入.
研究的目的:
- 评估通过前阴道静脉方法进行的AVS的成功率和安全性.
- 评估前静脉接入的可行性,作为腿部接入的替代方案.
主要方法:
- 对1226名患有原发性阿尔多斯特隆症的患者进行了回顾性多中心研究,这些患者接受了AVS.
- 在2012年1月至2018年12月期间,通过前静脉访问进行AVS分析.
- 通过选择性指数定义的成功 (上腺静脉中的皮质醇/IVC中的皮质醇) > 2.
主要成果:
- 实现了双边 (91.5%),右边 (94.9%) 和左边 (95.1%) 抽样的高成功率.
- 随着后续案件的成功率有所提高,这表明了学习曲线.
- 观察到低并发症率 (0.41%的上腺静脉破裂) 没有后果.
结论:
- 通过子宫前置方法进行AVS是一种安全且可行的程序.
- 这种方法证明了诊断原发性阿尔多斯特主义的成功率很高.
- 阴茎前方的方法作为一个潜在的替代品,以 access.femoral静脉.
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