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开发和验证用于预测血捐献后血管反应风险的诺米克图

Peizhe Zhao^1,2,3, Demei Dong⁴, Rong Dong⁵

¹Department of Blood Transfusion, Taiyuan Blood Center, Taiyuan, Shanxi Province, People's Republic of China.

Journal of clinical apheresis

|July 19, 2023

概括

血捐献后的血管道反应 (VVRs) 通过新模型预测. 这个工具可以识别高风险的捐赠者,提高血捐赠的安全性,并鼓励未来的捐赠.

科学领域:

输血医学输血医学
临床血液学临床血液学
公共卫生公共卫生

背景情况:

血管道反应 (VVRs) 是血捐赠中常见的不良事件.
视频回血器可以降低捐赠者返回率,影响血液供应.
识别风险因素对于捐赠者的安全和保留至关重要.

研究的目的:

调查与VVRs血捐赠后相关的因素.
开发一种预测性血红图,用于识别有风险的血捐赠者.
提高血捐献过程的安全性和效率.

主要方法:

分析了2019年7月至2020年6月期间的120448例血捐赠.
使用后勤回归识别VVR的独立风险因素.
预测名ogram模型的构建和验证.

主要成果:

VVR的发生率为0.66% (737/120,448次捐赠).
独立的风险因素包括性别,季节,捐赠者身份,体重,脉,捐赠时间和周期.
预测模型表现出高准确度 (C指数=0.916) 和良好的校准.

结论:

开发了一种实际的诺莫格拉姆模型,用于预测血捐赠后的VVR.
该模型有效地识别了对VVR风险较高的个体.
这种工具可以提高捐赠者的安全性,并可能增加捐赠频率.

关键词:

捐赠者的健康捐赠者的健康这个名字是名ogramogram.血捐赠血捐赠血捐赠预测模型预测模型血管血管反应的反应

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