在下肢肉 Sarcoma 开放对核心针检查:当前的实践模式和患者的结果
Zachary D C Burke1,2, Alexander L Lazarides1,3, Manit K Gundavda1,4
1University of Toronto Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Sinai Health System, Toronto, Ontario, Canada.
The Journal of bone and joint surgery. American volume
|July 19, 2023
概括
核心针活检 (CNB) 现在比瘤诊断的开放活检 (OB) 在国际上更为常见. 虽然OB导致了更长的手术和更多的组织去除,但与CNB相比,它不会增加感染或复发风险.
科学领域:
- 在瘤学瘤学.
- 手术病理学手术病理学
- 临床研究 临床研究
背景情况:
- 开放式活检 (OB) 从历史上来看是诊断肉瘤的标准.
- 核心针活检 (CNB) 越来越多地被使用,但它对手术结果的影响尚未明确.
研究的目的:
- 分析国际上的肉瘤活检实践模式.
- 为了比较OB与CNB对手术切除,感染风险,瘤结果和功能评分的影响.
主要方法:
- 对前性多中心PARITY研究的二次分析.
- 包括来自12个国家的48个中心的464名患者.
- 使用统计测试和1年后续对OB和CNB组之间的结果进行比较.
主要成果:
- CNB是占主导地位的活检方法 (57.5%),尽管OB在美国和加拿大更频繁.
- OB病例的手术时间 (324分钟而不是260分钟) 显著长,组织切除率更高.
- 在OB和CNB组之间,在手术部位感染或1年后的瘤结果中没有发现显著差异.
结论:
- 核心针活检是全球更常见的肉瘤活检技术.
- 开放式活检导致更长的手术时间和更多的组织去除,但不会对感染率或瘤结果产生负面影响.
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