成年人的上呼吸道形态与位置阻塞性睡眠呼吸暂停
Xiaoxin Shi1,2,3, Kate Sutherland4,5, Frank Lobbezoo6
1Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, the Netherlands. x.shi@acta.nl.
Sleep & breathing = Schlaf & Atmung
|July 19, 2023
概括
位置性阻塞性睡眠呼吸暂停 (POSA) 和非位置性阻塞性睡眠呼吸暂停 (NPOSA) 的成年人具有相似的上呼吸道解剖学. 这一发现表明位置因素,而不是气道形状,可能会影响POSA的发展.
科学领域:
- 人体解剖学 解剖学 解剖学
- 睡眠医学 睡眠医学
- 放射学 放射学是一门学科.
背景情况:
- 阻塞性睡眠呼吸暂停 (obstructive sleep apnea,OSA) 是一种常见的疾病,其特点是睡眠期间呼吸道缩.
- 位置性OSA (POSA) 是一种亚型,其中呼吸道阻塞主要与睡眠位置有关.
- 了解POSA和非位置性OSA (NPOSA) 之间的解剖学差异对于有针对性的治疗至关重要.
研究的目的:
- 为了在POSA和NPOSA的成年人之间比较上呼吸道的解剖平衡和卧卧姿势的形状.
- 调查卧卧姿的不同解剖特征是否区分POSA和NPOSA.
主要方法:
- 形束计算断层扫描 (CBCT) 用于对卧卧的OSA患者的上呼吸道进行成像.
- 解剖平衡是通过舌头大小与上关腔大小的比率来评估的.
- 上呼吸道的形状是通过在最狭窄的点上前后与侧面尺寸的比率来量化.
主要成果:
- 该研究包括47名患有OSA的成年人,其中72%被归类为POSA.
- 在对性别和AHI进行控制后,在POSA和NPOSA组之间没有发现解剖平衡或上呼吸道形状 (CSAmin形状) 的显著差异.
- POSA组显示出更高男性比例和更低AHI的趋势,尽管在统计学上并不显著.
结论:
- 患有POSA和NPOSA的成年人表现出相似的上呼吸道解剖平衡和形状,当躺卧时.
- 这些发现表明,呼吸道结构的解剖学变异可能不是区分POSA和NPOSA的主要决定因素.
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