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对于儿科囊性赤道球菌病的阿尔本达单疗法:一个病例系列

Moshe Shmueli¹, Siham Elamour^1,2, Orli Sagi³

¹The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Acta parasitologica

|July 19, 2023

概括

阿尔本达单一治疗对儿科囊性赤道球菌 (CE) 有效,特别是在小肝囊中. 这种治疗在大多数儿童中显示出囊大小的减少,失败率低.

科学领域:

寄生虫学的寄生虫学
儿童传染病儿童传染病
药物治疗药物治疗

背景情况:

有限的数据存在于阿尔本达单一治疗儿科囊性球菌 (CE).
本研究报告了使用阿尔本达单独治疗儿童CE治疗的经验.

研究的目的:

评估阿尔本达单一治疗在患有CE的儿童中的疗效和安全性.
确定影响儿科CE患者治疗决策和治疗结果的因素.

主要方法:

从2005年到2021年进行的回顾性案例系列.
包括18名患有31个CE囊 (主要是肝脏和肺部) 的儿科患者.
评估人口统计学,临床,治疗持续时间,随访,囊大小变化和不良事件.

主要成果:

阿尔本达单一治疗用于小囊 (<4厘米),难以手术的病例和并发症.
83%的患者没有表现出囊的生长,而72%的患者经历了囊大小的减少,44%>50%的减少.
22%的囊完全消失;17%的治疗失败 (复发/增长).
副作用包括中性质减退 (11%) 和肝酶升高 (33%).

结论:

单独使用阿尔本达治疗可以为特定的儿科CE病例提供适当的治疗.
它特别适合CE涉及小,肝脏囊.
建议对患者进行仔细的选择和监测.

关键词:

阿尔本达 (Albendazole) 是一种一种化疗化疗是一种化学疗法.埃奇诺科科菌病 (echinococcosis) 是一种虫病.酸体囊 (Hydatid cyst) 是一种酸体囊.儿科儿科儿科

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