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在骨淋巴结解剖时,骨淋巴结的阳性反向映射骨淋巴结:双侧前性试验

Molly M Benolken¹, Sarah McLaughlin¹, Mara Piltin²

¹Division of Surgical Oncology, Mayo Clinic, Jacksonville, FL, USA.

Annals of surgical oncology

|July 19, 2023

概括

在接受股淋巴结解剖 (ALND) 的患者中,股逆映射 (ARM) 淋巴结 (LNs) 的阳性率很高. 这表明,保留ARM LNs可能会损害淋巴结胀预防策略中的瘤安全性.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
淋巴 edem 研究研究淋巴 edem 研究

背景情况:

轴心逆向映射 (ARM) 是为了在轴心淋巴结解剖 (ALND) 期间保护上肢淋巴细胞而开发的,旨在减少淋巴风险.
在ALND患者中保存ARM淋巴结 (LNs) 的瘤安全性尚不清楚.
这项研究研究了ALND.接受治疗的患者中ARM LNs的转移性参与.

研究的目的:

为了确定 ARM LNs 中转移性参与的频率.
评估ALND期间保存ARM LNs的瘤安全性.
确定 ARM LN 保存可行的患者群体.

主要方法:

一项前性试验招募了在2018年4月至2022年12月期间接受ALND的患者.
分析的重点是ILR干预手臂的ARM节点阳性和总LN阳性率.
139名患者 (133名乳腺癌患者) 符合纳入标准.

主要成果:

在55名具有特定ARM节点的患者中,70.9%的患者在ALND.上呈阳性LNs.
在这些患者中,20% (11/55) 的ARM LNs呈阳性.
在11名阳性ARM LNs患者中,ARM LNs是3名患者的唯一阳性节点.

结论:

在接受ALND的当代患者中,ARM LN阳性率相对较高.
在ALND期间保存ARM LNs可能不具有瘤安全性.
需要进一步的研究来完善患者选择ARM LN保存的方法.

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