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Updated: Jul 23, 2025

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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准KRAS突变的NSCLC:新的技术知识和超越

David J Cantor1, Charu Aggarwal1,2,3

  • 1Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Clinical cancer research : an official journal of the American Association for Cancer Research
|July 19, 2023
PubMed
概括

具有KRAS突变的非小细胞肺癌 (NSCLC) 缺乏有效的向疗法. 过去的MEK抑制剂和化疗组合失败,需要针对这种常见的癌症亚型制定新的治疗策略.

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