Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

11.3K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
11.3K
RNA-seq03:21

RNA-seq

10.1K
RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
10.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Electrical discrimination of lysine methylation states at the single-molecule level.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026
Same author

Single-molecule detection of amino acid phosphorylation using electron tunnelling currents: toward neurodegenerative disease diagnosis.

Nanoscale·2026
Same author

Beyond ensemble averages: single-entity approaches for complex systems.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026
Same author

Rapid diagnosis of ocular viral infections via single-virus detection using solid-state nanopore: A diagnostic evaluation study.

PNAS nexus·2025
Same author

Anion vacancies activate N<sub>2</sub> to ammonia on Ba-Si orthosilicate oxynitride-hydride.

Nature chemistry·2025
Same author

Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment.

Nature communications·2024

相关实验视频

Updated: Jul 23, 2025

Production and Targeting of Monovalent Quantum Dots
10:16

Production and Targeting of Monovalent Quantum Dots

Published on: October 23, 2014

25.6K

使用量子计算机对核酸的单分子识别.

Masateru Taniguchi1, Takahito Ohshiro1, Tomofumi Tada2

  • 1SNAKEN, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047 Japan.

The journal of physical chemistry. B
|July 19, 2023
PubMed
概括

量子计算现在可以识别单个DNA核酸,这是个性化医学的关键一步. 这一突破使得使用量子计算机进行更快的基因组分析,用于医疗创新.

科学领域:

  • 量子计算是一种量子计算.
  • 基因组学就是基因组学.
  • 生物技术是生物技术.

背景情况:

  • 基因组信息对人类健康至关重要.
  • 量子计算为分析大型基因组数据集提供了潜力.
  • 目前的量子计算应用还没有包括基因组分析,例如核酸识别.

研究的目的:

  • 使用量子计算机演示单分子核酸识别.
  • 设计一个能够区分四个DNA核酸之间的量子门.
  • 为量子增强基因组分析奠定基础.

主要方法:

  • 设计了一个量子门来模拟腺的电子导电性.
  • 开发了一种包含反向和编码门的量子电路.
  • 利用量子计算进行单分子导电分析.

主要成果:

  • 通过使用量子计算机成功证明了核酸的单分子识别.
  • 设计的量子门有效地将腺与其他核酸区分开来.
  • 建立了能够进行核酸分化的量子电路.

结论:

更多相关视频

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA
12:35

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA

Published on: November 14, 2017

9.5K
Author Spotlight: Advancements in DNA Nanosensors &#8211; Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

1.0K

相关实验视频

Last Updated: Jul 23, 2025

Production and Targeting of Monovalent Quantum Dots
10:16

Production and Targeting of Monovalent Quantum Dots

Published on: October 23, 2014

25.6K
Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA
12:35

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA

Published on: November 14, 2017

9.5K
Author Spotlight: Advancements in DNA Nanosensors &#8211; Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

1.0K
  • 这项研究展示了通过量子计算进行单分子核酸鉴定的第一个实例.
  • 开发的量子门和电路对于推进量子基因组分析至关重要.
  • 这些发现代表了实现量子加速个性化医学和药物发现的重要一步.