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Updated: Jul 23, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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一个短的阿尔戈纳特-TIR原生物免疫系统的激活机制

Dongchun Ni1, Xuhang Lu2, Henning Stahlberg1

  • 1Laboratory of Biological Electron Microscopy, IPHYS, SB, EPFL, and Dept. Fundamental Microbiology, Faculty of Biology and Medicine, UNIL, Cubotron, Rt. de la Sorge, 1015 Lausanne, Switzerland.

Science advances
|July 19, 2023
PubMed
概括

短 prokaryotic argonaute (SPARTA) 复合体通过感知外来DNA/RNA来保护细菌. 结构研究揭示了SPARTA如何激活,导致细胞死亡和宿主免疫力.

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