两种版本的身体成分监测器之间的生物阻抗衍生流体状态的差异
Sebastian Mussnig1, Michael Schmiedecker1, Maximilian Waller2
1Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Nutrition (Burbank, Los Angeles County, Calif.)
|July 19, 2023
概括
较新的身体成分监测 (BCM) 版本3.3.3显示,与版本3.2.5.5相比,过度水分 (OH) 测量有临床显著差异. 确保一致的BCM设备版本,以准确监测患者.
科学领域:
- 医疗器械 医疗器械
- 生物医学工程 生物医学工程
- 临床监测 临床监测
背景情况:
- 身体成分监测器 (BCM) 用于评估身体成分,包括液体状态和过度水分 (OH).
- 医疗器械的不同软件版本可能会导致测量结果的变化.
研究的目的:
- 为了研究和量化两个版本的身体组成监测器 (BCM) 之间的身体组成和过度水分 (OH) 测量差异:版本3.2.5和版本3.3.3.
- 评估BCM测量中任何观察到的差异的临床相关性.
主要方法:
- 28名血液透析患者在连续14次透析疗程之前使用3.2.5和3.3.3版本的设备进行BCM测量.
- 配对威尔科克森试验被用于统计分析BCM设备之间的差异,不包括集群数据.
- 阻抗数据,特别是细胞内电阻 (Ri) 和时间延迟 (T<0xE1><0xB5><0xA1>),被分析以确定光谱差异.
主要成果:
- 在数据清洗后,共分析了27名患者的288个测量对.
- 与3.2.5版本相比,3.3.3版本显示过度水分 (OH) 的平均差异为0.548L,表明OH.
- 在高频阻抗谱中发现了统计学上显著的差异,包括细胞内电阻 (Ri) 和时间延迟 (T<0xE1><0xB5><0xA1>) (P <0.001).
结论:
- 结果表明BCM版本3.2.5和3.3.3.之间的临床上有意义的差异.
- 新版本的3.3.3显示了对低估过度水分 (OH) 的偏见.
- 建议验证BCM设备版本,并为每个患者使用一致的版本,以确保可靠的患者内测量.
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