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Updated: Jul 23, 2025

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations
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Published on: March 29, 2017

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MYD88L265P通过与DOCK8的相互作用,在大型B细胞淋巴瘤中增加了近端B细胞受体信号传递

Elisa Mandato1, Qingsheng Yan1, Jing Ouyang1,2

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.

Blood
|July 19, 2023
PubMed
概括

在MYD88和CD79B的突变增强B细胞受体信号在扩散性大B细胞淋巴瘤 (DLBCL). 这种涉及DOCK8的交叉解释了DLBCL对布鲁顿氨酸激酶 (BTK) 抑制剂的敏感性.

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