一个目标发现管道确定ILT3作为多发性骨髓瘤免疫治疗的目标

Francesco Di Meo1, Anjushree Iyer2, Keith Akama2

  • 1Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

PubMed
概括

研究人员通过分析细胞表面蛋白质,确定了多发性骨髓瘤 (MM) 免疫治疗的有希望的新点. 一种针对ILT3的新型双特异性T细胞吸引剂在临床前模型中显示出显著的抗癌作用,为有效的MM治疗提供了希望.

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