神经放射学诊断中的动脉脊柱标记 (ASL) - 方法概述和使用案例
Nico Sollmann1,2,3,4, Gabriel Hoffmann2,3, Severin Schramm2
1Department of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
|July 19, 2023
概括
动脉旋转标记 (ASL) 是用于脑 perfusion 成像的MRI 技术,评估没有对比剂的脑血流 (CBF). 它对各种中枢神经系统疾病和特定患者群体显示出前景.
科学领域:
- 磁共振成像 (MRI) 是一种磁共振成像技术.
- 神经成像技术的神经成像技术
- 大脑输液评估
背景情况:
- 动脉旋转标记 (ASL) 使用标记的血液水作为脑 perfusion 成像的内源性标记物.
- 通过ASL,可以进行大脑血流 (CBF) 的非侵入性评估.
研究的目的:
- 提供ASL技巧的方法和技术概述.
- 突出ASL在中枢神经系统 (CNS) 疾病中的临床应用.
- 专注于最近的进展,如超选择性ASL (ssASL) 和基于ASL的时间解析MRA.
主要方法:
- 审查ASL的方法和技术方面.
- 检查各种中枢神经系统病理的临床用例.
- 包括最近的发展,如ssASL和基于ASL的MRA.
主要成果:
- 来自ASL的CBF是脑血管疾病,瘤和神经退行性疾病的临床相关参数.
- ASL可以识别轻度创伤性脑损伤和偏头痛等疾病的生物标志物.
- ssASL可实现空间 perfusion 区域映射,而基于 ASL 的 MRA 可提供时间解析的血管划分.
结论:
- ASL输液成像显示出各种中枢神经系统疾病的显著前景.
- ASL是有利的,因为它避免了基于加多的对比剂,使特定的患者群体受益.
- 对于儿科患者,患有功能障碍,过敏或需要连续监测的人来说,ASL特别有价值.
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