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Updated: Jul 23, 2025

TGF-β-mediated Endothelial to Mesenchymal Transition EndMT and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing
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通过PPARγ下调调节,机械应力诱导了内皮细胞中的EndoMT

Gang Dong1, Xiaoquan Huang1, Ye Xu2

  • 1Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.

Cellular signalling
|July 19, 2023
PubMed
概括

在门高血压中,机械拉伸会减少内皮细胞中PPARγ的表达,从而触发内皮细胞转变为介质细胞. 罗西格利塔治疗逆转了这些影响,提供了一个潜在的治疗策略.

关键词:
欧洲共同体 (ECs) 是一个欧洲共同体.在EndoMTMT中使用.机械拉伸是一种机械拉伸.在PPARγ中,PPARγ是PPARγ门口高血压的高血压.罗西格利塔 (Rosiglitazone) 是一种有毒的药物.

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