一项试点研究:探索COVID-19对心血管生理学和视网膜微循环的影响
Adam Saloň1, Ruslan Neshev2, Kaja Teraž3
1Division of Physiology & Pathophysiology, Otto Loewi Research Center for Vascular Biology, Immunology, and Inflammation, Medical University of Graz, Austria; Faculty of Health and Social Sciences, Inland Norway University of Applied Sciences, Lillehammer, Norway.
Microvascular research
|July 19, 2023
概括
在COVID-19康复后的几周内,心血管变化仍然存在. 这项研究观察到感染后患者的血压升高和视网膜静脉狭窄,表明正在进行的血管适应.
科学领域:
- 心血管医学 心血管医学
- 传染性疾病 传染性疾病
- 血管生物学 血管生物学
背景情况:
- 已知严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 影响心血管系统.
- 了解COVID-19后心血管后果对于患者管理至关重要.
研究的目的:
- 为了研究2019年新冠病毒病 (COVID-19) 康复的患者的心血管变化.
- 评估感染后心率 (HR),血压 (BP),脉冲波速度 (PWV) 和微循环的变化.
主要方法:
- 35名COVID-19患者在两个时间点进行了监测:出院后的基线和住院后的60天.
- 血管测量包括使用VICORDER®的HR,BP,PWV,以及视网膜血管分析 (CRVE,CRAE).
主要成果:
- 系统血压 (SBP) 的显著增加和心率 (HR) 的显著降低被观察到.
- 发现了视网膜中枢静脉等效 (CRVE) 的显著缩小,这表明了微血管变化.
- 趋势表明PWV的增加和中枢视网膜动脉等效 (CRAE) 的减少.
结论:
- 心血管适应,包括BP,HR和微血管结构的变化,在COVID-19住院治疗后的几周内仍在继续.
- 这些发现凸显了COVID-19感染的长期血管影响的潜力.
- 建议在感染期间和感染后进行临时评估,进行进一步的研究.
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